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Monday, April 29, 2013

Patterned hearts: Bioengineers create rubber-like material bearing micropatterns for stronger, more elastic hearts

Apr. 29, 2013 ? A team of bioengineers at Brigham and Women's Hospital (BWH) is the first to report creating artificial heart tissue that closely mimics the functions of natural heart tissue through the use of human-based materials. Their work will advance how clinicians treat the damaging effects caused by heart disease, the leading cause of death in the United States.

"Scientists and clinicians alike are eager for new approaches to creating artificial heart tissues that resemble the native tissues as much as possible, in terms of physical properties and function," said Nasim Annabi, PhD, BWH Renal Division, first study author. "Current biomaterials used to repair hearts after a heart attack and other cardiovascular events lack suitable functionality and strength. We are introducing an alternative that has the mechanical properties and functions of native heart tissue."

The study was published online on April 26, 2013 in Advanced Functional Materials.

The researchers created MeTro gel-an advanced rubber-like material made from tropoelastin, the protein in human tissues that makes them elastic. The gel was then combined with microfabrication techniques to generate gels containing well-defined micropatterns for high elasticity.

The researchers then used these highly elastic micropatterned gels to create heart tissue that contained beating heart muscle cells.

"The micropatterned gel provides elastic mechanical support of natural heart muscle tissue as demonstrated by its ability to promote attachment, spreading, alignment, function and communication of heart muscle cells," said Annabi.

The researchers state that MeTro gel will provide a model for future studies on how heart cells behave. Moreover, the work lays the foundation for creating more elaborate 3D versions of heart tissue that will contain vascular networks.

"This can be achieved by assembling tandem layers of micropatterned MeTro gels seeded with heart muscles cells in different layers," said Ali Khademhosseini, PhD, BWH Division of Biomedical Engineering, co-senior study author. "As we continue to move forward with finding better ways to mend a broken heart, we hope the biomaterials we engineer will allow us to successfully address the limitations of current artificial tissues."

This research was supported by the National Institutes of Health (HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392); National Health and Medical Research Council; CRC for Polymers; BHP-Billiton Fulbright Scholarship; National Science Foundation; Office of Naval Research Young National Investigator Award; Presidential Early Career Award for Scientists and Engineers; Australian Research Council; and Australian Defense Health Foundation and National Health and Medical Research Council.

Anthony Weiss, PhD, University of Sydney, co-senior study author is scientific founder of Elastagen Pty Ltd.

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The above story is reprinted from materials provided by Brigham and Women's Hospital.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Nasim Annabi, Kelly Tsang, Suzanne M. Mithieux, Mehdi Nikkhah, Afshin Ameri, Ali Khademhosseini, Anthony S. Weiss. Highly Elastic Micropatterned Hydrogel for Engineering Functional Cardiac Tissue. Advanced Functional Materials, 2013; DOI: 10.1002/adfm.201300570

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/biochemistry/~3/OQiD_HD9WH0/130429133652.htm

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Suicide Bombing Kills 6, Wounds Dozens In Northwest Pakistan

PESHAWAR, Pakistan ? A suicide bomber targeting a police van killed six people in northwestern Pakistan on Monday, including the son and nephew of an Afghan official involved in peace negotiations with the Taliban, officials said.

The bomber, who was riding a motorcycle, detonated his explosives as the police patrol drove by in the northwestern city of Peshawar, said city police chief Liaqat Ali Khan.

The two Afghans who were killed ? Qazi Mohammad Hilal Waqad and Mohammad Idrees ? were working at their country's consulate in Peshawar where the attack occurred, said Afghan Consul General Syed Mohammad Ibrahim Khel in Islamabad.

However, it did not appear they were the target of the attack, Khel said.

Waqad's father, Qazi Amin Waqad, is a member of the Afghan High Peace Council, a group appointed by the Afghan government to hold peace negotiations with the Taliban, said an official at the consulate in Peshawar, Shakir Qarar.

The peace council member was in Afghanistan when the attack occurred, while Waqad and Idrees were driving to work when the bomber struck, Qarar added.

Three policemen were among over 30 people who were wounded by the blast, said the police chief, Khan. Many of the dead and wounded were from a nearby passenger bus, which bore the brunt of the attack.

Local TV footage showed the wreckage of the bus and the motorcycle, as rescue workers rushed wounded people to hospitals in the city.

No one immediately claimed responsibility, but suspicion will likely to fall on the Pakistani Taliban. The group has been waging a bloody insurgency against the government for years and has stepped up attacks ahead of next month's parliamentary election.

On Sunday, the Taliban killed 11 people in bomb attacks on a political rally and two campaign offices in the northwest, part of their quest to disrupt the election. The group has killed at least 60 people in attacks on politicians and party workers since the beginning of April.

The Taliban have specifically targeted more secular political parties that have supported military offensives against the militants in the northwest. The Taliban have largely spared Islamic parties and others who believe the government should strike a peace deal with the militants, rather than fight them.

There is a concern that the violence could benefit the parties that take a softer line toward the militants because they are able to campaign more freely ahead of the May 11 election.

"Unless the government, the country's independent election commission and security forces ensure that all parties can campaign freely without fear, the election may be severely compromised," Ali Dayan Hasan, the head of Human Rights Watch in Pakistan, said in a statement issued Monday.

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Source: http://www.huffingtonpost.com/2013/04/29/pakistan-suicide-bombing-peshawar_n_3176388.html

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Inbee Park wins North Texas LPGA, 3rd win in '13

IRVING, Texas (AP) ? Inbee Park was already preparing to congratulate Carlota Ciganda for winning the inaugural North Texas LPGA Shootout.

Park, the top-ranked woman in the world, was in the middle of a solid final round and still trailed by two strokes after the playing partners both had birdies at the par-5 10th on Sunday.

Everything changed in a two-hole stretch, when Park went ahead with consecutive pars. The 24-year-old South Korean went on to a bogey-free 4-under 67 that put her one stroke ahead of Ciganda, good enough for her third victory this season and fifth in her last 18 starts.

"She was hitting fairways and greens and making putts," said Park, who finished at 13 under. "And I thought I played really great today, but I just missed a lot of birdie opportunities, so I thought this tournament might not be mine because I missed that many opportunities and Carlota was playing great golf. But she made a couple mistakes on the back nine."

Ciganda's drive at the 416-yard 14th hole settled in the right rough with a tree between her and the green, and her shot from about 130 yards clipped a branch and came up short. She had a chance to save par but her 6-foot putt was short, and Park's par had her within a stroke of the lead.

After stepping away from her approach at No. 15, to a green surrounded by water on three sides, Ciganda hit a shot that went to the right and then rolled down into the water. Ciganda had to go back to a drop zone, where the 22-year-old Spaniard had a decent pitch before her first putt rolled over the left edge of the green for a double bogey 6.

Park had another par and never trailed again.

"I'm very happy with my round and with my week. ... I had two bad holes on the back nine," Ciganda said.

With the $195,000 check for first place, Inbee exceeded $6 million in career earnings and will be No. 1 for the third week in a row. It was her sixth career LPGA victory, along with four more wins in Japan.

Fifth-ranked Suzann Pettersen from Norway, the winner in Hawaii last week, had a closing 66 to get to 10 under and finish third. Hee Young Park (64) and So Yeon Ryu (68) tied for fourth at 275.

Ciganda played last season on the Ladies European Tour, where she was the top rookie and the top money winner ? the first player since Laura Davies in 1985 to accomplish that feat. She won twice in Europe last year and now has her best LPGA finish.

At the 403-yard 8th hole, Park made a birdie before Ciganda followed with one of her own and responded with a slight fist pump when her ball dropped into the cup. They both had pars at No. 9, where Park was closer to the hole even though she was missed the green to the left, and they traded birdies again at the par-5 10th.

"I was happy and playing good and having fun and enjoying the day," said Ciganda, who had a closing 70. "And then I think, let me see, the hole it bounced to the right, but I had a bogey there and then hit it to the water on 15."

Caroline Masson had a 75 and finished eight shots back. The LPGA Tour rookie from Germany led after each of the first two rounds and started the final round tied for second with Park.

Hee Young Park's 64 was the best round of the day on the 6,439-yard course with plenty of sloping fairways and raised greens.

Stacy Lewis, the Texas native and No. 2 player in the world, had a closing 66 when all six birdies and her only bogey came between Nos. 7-17. She tied for seventh for her sixth top-10 finish this season.

At the end of her round, Lewis signed the back brace of a 6-year-old Dallas girl who was diagnosed with scoliosis at 18 months old. Lewis wore a similar brace 18 hours a day for seven years after being diagnosed with scoliosis at age 11 and missed her first collegiate season after a spinal fusion.

Third-ranked Na Yeon Choi, among the four players tied for seventh, had 44 consecutive bogey-free holes and was 9 under before consecutive bogeys at Nos. 10-12. She went on to a 72.

Inbee Park sank a 4-foot birdie putt on the par-5 18th after Ciganda also birdied even after her final drive went into the right rough. But they had an unusual wait after hitting their drives, when Jee Young Lee, playing two groups ahead of them, had to replay the hole.

Before Lee signed her scorecard, officials determined she took an improper drop after her drive at No. 18 went out of bounds. Lee carded a 10 before Ciganda and Park got to play out the hole.

"It was all right. I mean it was actually really good, it ended up really good for me because I made a birdie," Park said of the delay. "Maybe if I hit it in the water maybe I could have blamed it on them."

Source: http://news.yahoo.com/inbee-park-wins-north-texas-lpga-3rd-win-220908451.html

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Xerox Phaser 7100/N

The Xerox Phaser 7100/N is a new model in Xerox's repertoire, filling a niche as a relatively low-cost color laser printer that can print at up to tabloid size (11 by 17 inches). In that role it's a winner, with good speed and strong output quality, led by above-par graphics and slightly above-average photos. It earns an Editors' Choice for budget color laser printer.

The 7100/N lacks the natural-language color control of the Editors' Choice Xerox Phaser 7500/DN and is not designed for as massive print volumes--with a maximum monthly duty cycle of 52,000 pages, compared with the 7500/DN's 150,000 pages. It can't quite match the 7500/DN's exceptional output quality. But it brings enough to the table to become an Editors' Choice in its own right as a lower-priced tabloid color laser printer.

The two-tone (blue and white) 7100/N measures 16 by 21 by 19.7 inches (HWD) and weighs 97 pounds, so you'll need at least two people to move it into place. Still, it's lighter than the 145-pound Xerox 7500/DN. The 7100/N has a 400-sheet standard paper capacity, between a 250-sheet main tray and a 150-sheet secondary tray, both of which can fit tabloid-size (11 by 7) paper. The 7100/N lacks an automatic duplexer; another model, the 7100/DN ($1,800 direct), includes a duplexer. Up to three additional 550-sheet trays ($399 each) are available as options, as is a wireless adapter ($219), and a productivity kit whose centerpiece is a 40GB hard drive ($499).

The Xerox Phaser 7100/N has standard Ethernet and USB connectivity. I tested the Phaser over an Ethernet connection with a PC running Windows Vista. The recommended driver, which installs by default, is PostScript; users can also install PCL emulations, PDF Direct, or XPS drivers. I ran all our tests using the default PostScript driver.

Xerox Phaser 7100/N

Speed
I timed the Xerox Phaser 7100/N on the latest version of our business applications suite (as timed with QualityLogic's hardware and software), at 7.6 effective pages per minute (ppm) a good speed considering its rated print speed of 30 ppm. (Rated speeds are based on text-only printing, while our test suite combines text pages, graphics pages, and pages with mixed content.) It even edges out the Xerox Phaser 7500/DN, rated at 35 pages per minute for both color and black-and-white printing, which we timed at 7.1 ppm. I clocked the Dell 7130cdn Color Printer , rated at 35 ppm for monochrome printing and 30 ppm for color printing, at 8.3 ppm.

Output Quality
The Phaser 7100/N's text was average for lasers, which is still good enough for most every business document except for uses such as demanding desktop publishing applications requiring very small fonts.

Graphics quality is above par; graphics should be fine for any internal business use, including PowerPoint handouts, and could be used for basic marketing materials. Flaws, all minor, included some mild blotchiness in dark backgrounds, and dithering (graininess).

Photo quality was slightly above average. Most of the prints could pass as true photo quality when seen under glass at arm's length. There was some loss of detail in bright areas, and one image showed traces of banding (spurious, slightly dark streaks). The quality is easily good enough to use in company or client newsletters, and is perhaps up to use in basic advertising handouts, depending on how picky you are.

Comparison
As a budget color laser that can print up to tabloid size, the Xerox Phaser 7100/N offers good speed and good overall output quality, with above-average graphics and slightly above-par photos. The 7100/N lacks natural language software color control, one of our favorite features from the Xerox 7500/DN. Accessible through the printer's drivers, it lets people with no technical knowledge of color mixing easily tweak colors from print to print by using a series of drop-down menus, with commands such as "green colors slightly more green."

The 7100/N's output quality?though solid, with particularly good graphics quality?can't match that of the 7500/DN, which was top tier for photos and graphics and just short of top tier for text. The 7500/DN also has great paper capacity (600 sheets standard, plus auto-duplexer). The 7100/N did manage to edge the 7500/DN in printing speed, however.

The Dell 7130cdn, essentially the same printer as the Xerox 7500/DN except lacking natural-language color control, is a tad faster than the other two printers. Its output quality was similar to the 7100/N's, except the Xerox printed superior graphics in our testing. And it costs more than $1,000 more than the 7100/N.

Although the Xerox Phaser 7100/N can't match the Phaser7500/DN in features and output quality, you can get it for less than half the price, a bargain for a tabloid color laser printer. So while the 7500/DN remains the Editors' Choice as a high-end color laser tabloid printer, the 7100/N is a new Editors' Choice as a budget model. Not only is it cost effective, it adds good speed and output quality, and should be a welcome addition to small or mid-sized offices or workgroups looking for a color laser that can print at tabloid size.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/zKrLRyydnzY/0,2817,2418241,00.asp

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Court: UK mother forced teen daughter to inseminate herself

By Estelle Shirbon

LONDON (Reuters) - A mother who persuaded her adopted teenage daughter to become pregnant by artificial insemination because she wanted a baby for herself has been jailed for five years in Britain, in a case that raises concern over how easily donor sperm can be obtained.

Previously secret court documents showed that the daughter, a virgin, was made to inseminate herself alone in her bedroom seven times over a two-year period starting in 2008 when she was 14, using syringes of semen bought online by the mother from sperm bank Cryos in Denmark.

She eventually became pregnant at 16 and gave birth at 17. The extraordinary circumstances of her pregnancy came to light after midwives became suspicious of the mother because she was trying to prevent her daughter from bonding with the new baby.

"We don't want any of that attachment thing," the mother said when a midwife suggested that the girl might want to breastfeed. After several such incidents the midwives alerted social services and police got involved in July 2011.

In a ruling made in March 2012 but only published now after the conclusion of the mother's criminal trial, High Court Judge Peter Jackson described "an abiding sense of disbelief that a parent could behave in such a wicked and selfish way towards a vulnerable child".

The judge also raised questions about the international trade in donor sperm, noting that "there were no effective checks on a person's ability to obtain sperm from Cryos".

There is no law in Britain to stop someone from buying donor sperm on the Internet and using it at home without supervision.

The Human Fertilisation and Embryology Authority (HFEA) said it was "shocked and appalled by this dreadful case" and would be discussing with the Department of Health the issues raised relating to the donation of sperm.

Described in the judgment as having "an exceptionally forceful personality", the mother wanted to be the sole influence in the lives of her daughters, whom she schooled at home behind drawn curtains and kept isolated from the world.

The mother, who was imprisoned for child cruelty, had three adopted daughters but desperately wanted a fourth and was distraught when authorities told her in 2007 that she would not receive approval for a further adoption.

Instead, she persuaded the eldest of her three daughters to embark on a program of artificial insemination to provide her with a baby to raise as her own.

The mother wanted the child to be a girl and made her daughter use acid douches containing vinegar or lemon juice in the belief that this would influence an unborn child's gender.

The daughter said she allowed her body to be used by her mother because she loved her. In a Mother's Day card written in 2009, the daughter pasted a photo of a positive pregnancy test and promised that she would give her mother that.

Cryos declined to comment on the case or on its procedures. In a section on home insemination, the sperm bank's website says: "In EU the goods can freely be moved from country to country, however, Cryos cannot know the rules in all countries so the recipient is responsible for the legality of imports."

(editing by Mike Collett-White)

Source: http://news.yahoo.com/mother-forced-daughter-14-sperm-insemination-uk-court-162645670.html

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What Luck! Hedgies Load Up on JCP Ahead of ... - Yahoo! Finance

The NY Post is reporting that "at least two major hedge funds" have amassed significant stakes in troubled, near dead, strategically challenged retailer JC Penney. The news comes on the heels of last week's SEC filing from George Soros revealing a 7.9% stake in JC Penney (JCP) stock.

Adding to the JC Penney positive news from earlier this morning, the company confirms it secured a $1.75 billion financing package from Goldman Sachs (GS). The terms have been rumored to be a remarkably generous 7%.

A whopping 36.8% of JC Penney's float was short as of April 15th. A big part of the short thesis had been the very real possibility that the company wouldn't have the liquidity to make it to the Christmas buying season.

Between the Post's unnamed funds and Soros, the timing of the stock purchases are curious if not flat out suspicious. JC Penney had been known to be looking for loans for months, and Goldman no doubt shopped the deal around the Street to find indications of interest.

JC Penney stock has been locked in the mid-teens for almost two months. So much smart money jumping in all at once is curious if not a smoking gun. Knowing the deal was likely to get done would have made the $15 area a low-risk entry point.

The company still has a laundry list of problems, but at least for the moment liquidity isn't one of them. "This company obviously has a lifeline now," says Yahoo Senior Columnist Michael Santoli in the attached clip. "You can kind of make the case that if JCPenney can at all stop the bleeding, maybe there's value there." Nothing beats a couple billion dollars at favorable rates when it comes to stanching a cash bleed.

"The stock bottomed, it looks now around $15 and now we're about $17 somewhere," notes Santoli, and that the company "really [hasn't] done much of anything but get out of that death-watch zone in terms of price." When a company has been as bad as JC Penney, achieving a stable vegetative state can be enough to take shares farther than would seem logical.

Source: http://finance.yahoo.com/blogs/breakout/luck-hedgies-load-jcp-ahead-debt-lifeline-150620255.html

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Obama White House Correspondents Dinner Speech Brought Laughs (VIDEO)

Chief of Staff Gen. Raymond T. Odierno, from left, Michael Scherer, White House correspondent for TIME, late-night television host Conan O'Brien and first lady Michelle Obama attend the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)

US-POLITICS-ENTERTAINMENT-WHCA-DINNER

Comedian Conan O'Brien (L) smiles as US President Barack Obama (C) and US first lady Michelle Obama arrive for the White House Correspondents? Association Dinner April 27, 2013 in Washington, DC. Obama attended the yearly dinner which is attended by journalists, celebrities and politicians. AFP PHOTO/Brendan SMIALOWSKI (Photo credit should read BRENDAN SMIALOWSKI/AFP/Getty Images)

Barack Obama

President Barack Obama looks to the podium during the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)

US-POLITICS-ENTERTAINMENT-WHCA-DINNER

Comedian Conan O'Brien (L) and US first lady Michelle Obama joke during the White House Correspondents? Association Dinner April 27, 2013 in Washington, DC. Obama attended the yearly dinner which is attended by journalists, celebrities and politicians. AFP PHOTO/Brendan SMIALOWSKI (Photo credit should read BRENDAN SMIALOWSKI/AFP/Getty Images)

Barack Obama, Conan O'Brien, Michelle Obama, Michael Clemente

Late-night television host Conan O'Brien, from left, first lady Michelle Obama, Michael Clemente, Executive Vice President of Fox News, and President Barack Obama attend the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)

US-POLITICS-ENTERTAINMENT-WHCA-DINNER

Comedian Conan O'Brien listens during the White House Correspondents? Association Dinner April 27, 2013 in Washington, DC. Obama attended the yearly dinner which is attended by journalists, celebrities and politicians. AFP PHOTO/Brendan SMIALOWSKI (Photo credit should read BRENDAN SMIALOWSKI/AFP/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Alicia Quarles attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Megan Hilt attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Morena Baccarin attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Musician John Legend attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Model Chrissy Teigen attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

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Entertainer John Legend arrives at the annual White House Correspondents' Association dinner in Washington DC, April 27, 2013. AFP Photo/ Chris KLEPONIS (Photo credit should read CHRIS KLEPONIS/AFP/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Musician Psy attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

Steven Spielberg

Director Steven Spielberg uses his smart phone during the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Amy Poehler attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Claire Danes attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Julia Louis-Dreyfus attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Kerry Washington attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Rebel Wilson and Olympic Gymnist Gabby Douglas attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Kate Mara attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Aasif Mandvi and Ty Burrel attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Al Sharpton and Chris Matthews attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Emily Mortimer attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Connie Britton attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Patricia Arquette attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: John Oliver and Kate Oliver attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actor Ryan Kwanten attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Jessica Pare attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actor Justin Bartha attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Julie Bowen attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: NFL player Victor Cruz (L) and Elaina Watley attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Ty Burrell attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Olivia Munn attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

TIME/CNN/PEOPLE/FORTUNE Pre-Dinner Cocktail Reception

WASHINGTON, DC - APRIL 27: Jeffrey Katzenberg, Time Magazine Managing Editor Rick Stengel and Steven Spielberg attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Larry Busacca/Getty Images for Time, Inc)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Elizabeth Banks attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Aasif Mandvi attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Sofia Vergara attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Michelle Dockery attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actress Constance Zimmer attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actor Tony Goldwyn attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Thomas Roberts attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Actor Ed Helms attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Korie Robertson and Willie Robertson attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

TIME/CNN/PEOPLE/FORTUNE Pre-Dinner Cocktail Reception

WASHINGTON, DC - APRIL 27: Gerard Butler and Piers Morgan attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Larry Busacca/Getty Images for Time, Inc)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Matthew Perry attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

2013 White House Correspondents' Association Dinner

WASHINGTON, DC - APRIL 27: Piers Morgan and Gerard Butler attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)

Source: http://www.huffingtonpost.com/2013/04/28/obama-white-house-correspondents-dinner_n_3158229.html

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