Apr. 29, 2013 ? It turns out the white-lipped peccary -- a piglike animal from Central and South America -- will settle for fish when fruits (its main food) are no longer on the menu, according to the Wildlife Conservation Society and partners revealing the first-ever photos of fish-eating peccaries.
The images of fish consumption by white-lipped peccaries were taken by Douglas Fernandes in the Brazilian Pantanal wetlands one morning back in 2011. A short description of the observations, along with the digital photographs taken, will appear in the latest edition of Suiform Soundings (IUCN Peccary Specialist Group Newsletter).
"As far as we know, these are the first images of fish consumption by white-lipped peccaries," said Dr. Alexine Keuroghlian of the Wildlife Conservation Society and an expert on peccaries. "This finding expands our knowledge of how this ecologically important species survives in highly seasonal habitats."
While there was one reported account by Dr. Joe Fragoso of the white-lipped peccary dining on fish in the Amazon, the behavior has been rarely seen and apparently never photographed until the morning of August 17, 2011. On that day, Fernandes, a researcher for the Instituto Arara Azul, a partner organization , observed a group of approximately 30 white-lipped peccaries at Caiman Lodge near the town of Miranda in the Pantanal, one of the world's largest tropical wetlands. Most of the peccaries fled as he approached, but five remained as they fed on aquatic plants in shallow ponds, created by the receding flood waters typical of the Pantanal's dry season. It was then that Fernandes noticed three of the peccaries eating traira, or wolf fish, from the oxygen-starved ponds.
"We know that peccaries are primarily fruit-eaters, but will consume aquatic plants, tubers, grasses, and small invertebrates, such as insect larvae, worms, and snails, when fruits are scarce," said Dr. Keuroghlian.
"At the time, I knew this was a rare observation but was unaware of the fact that I was taking perhaps the first images of this behavior," said Fernandes.
The white-lipped peccary is a medium-sized animal that occurs in both humid tropical forests as well as open savanna and wetland habitats throughout Central and South America. The species sometimes travels in herds of hundreds of individual animals, the only Neotropical ungulate (hoofed mammal) known to do so. As a major fruit-eater, the white-lipped peccary plays an important ecological role in rainforests and other habitats as a seed predator and disperser, and it is a favorite prey of jaguars and pumas. Additionally, white-lipped peccaries are considered an environmental indicator of a well-preserved forest.
The white-lipped peccary is listed as "Near Threatened"on the IUCN's Red List, but its status is currently under review as "Vulnerable." The two main threats faced by white-lipped peccaries are habitat loss and direct hunting.
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ARLINGTON, Va. (AP) ? The eternal flame at the gravesite of former President John F. Kennedy is undergoing repairs at Arlington National Cemetery.
Before the repairs began, workers used a torch Monday to carry the flame and pass it to a temporary burner that will be visible to tourists at the site while work is underway.
Cemetery officials say the work will take about three weeks and should be completed by late May, when the flame will be passed back to the original site.
A temporary flame was used from the time of Kennedy's November 1963 funeral until the permanent flame was established in 1967. Officials said repairs are needed after more than four decades of use and will include new gas lines and more efficient burners.
We knew CrunchBase was big. We knew because there are 2 million people using the startup database each month. We knew because more than 120k people have contributed 1.6MM data points on companies, entrepreneurs, fundings, exits and more. What we didn't know, however, was what the investment community thinks about CrunchBase.
GAZA CITY, Gaza Strip (AP) ? An Israeli aircraft attacked a motorcycle in Gaza on Tuesday, killing a man who the military said was a top militant in a shadowy al-Qaida-influenced group who had been involved in a recent rocket attack on southern Israel.
It was the first deadly airstrike in Gaza since a truce was reached with Palestinian militants last November, and is the most serious test yet of the Egyptian-brokered agreement.
The strike came alongside the fatal stabbing of an Israeli settler in the West Bank, the first killing by a Palestinian of an Israeli in the territory in more than a year.
The aircraft hit the motorcycle northwest of Gaza City, killing the driver and wounding a passenger. A bystander was also wounded, according to Gaza medical officials.
The Israeli military said it killed Haitham Mishal, describing him as a jihadi militant involved in an April 17 rocket attack on the southern Israeli resort town of Eilat and other violence. Ashraf al-Kidra, Gaza's Health Ministry spokesman, said Mishal was a policeman.
Israeli Prime Minister Benjamin Netanyahu warned recently that Israel would not tolerate rocket fire from either the Gaza Strip or Egypt's Sinai desert.
"We hit today one of those involved in the despicable rocket fire on Eilat. I said that we would not be quiet over that," Netanyahu said Tuesday.
Tuesday's airstrike showed strains in a five-month cease fire brokered by Egypt last November that ended eight days of exchanges between Israel and Hamas. Under the deal, Gaza militants pledged to halt rocket attacks on Israel, while Israel said it would end its policy of assassinating wanted militants.
After months of relative calm, the truce has begun to unravel. Palestinian militants have sporadically fired rockets into southern Israel in recent weeks. The Israeli air force has responded with strikes on training sites and suspected weapons storage sites in Gaza. Until Tuesday, there had been no casualties.
In a statement, the Israeli military said Mishal was involved in the Mujahideen Shura Council in the Environs of Jerusalem, a murky al-Qaida-inspired group that has claimed responsibility for a number of rocket attacks, including the Eilat incident.
Israel viewed the rocket attack on Eilat, a normally tranquil oasis that borders the Red Sea and Egypt's Sinai desert, as an escalation. It accused Gaza militants of firing the rockets, which caused no injuries, out of Egypt's lawless Sinai desert.
It said Mishal "has been a key terror figure, specializing in weapons and working with all of the terror organizations in the Gaza Strip." It said he manufactured weapons and specialized in rockets and explosive devices that he sold to militant groups.
Hamas, the Islamic militant group that rules Gaza, condemned the Israeli attack but also signaled that it is eager to preserve the truce.
"We call on Egypt to put pressure on the Israeli occupation to stop these crimes and to force them to honor the truce and stop the aggression," said Hamas spokesman Fawzi Barhoum. He called for a "joint and unified" effort by Gaza's various militant factions.
Hamas considers the jihadi groups responsible for recent rocket fire to be rivals, and has struggled to keep them in check. Since the cease-fire was reached, Hamas has deployed security forces along the border areas with Israel and Egypt to help preserve the calm.
In the West Bank, meanwhile, a Palestinian man fatally stabbed an Israeli waiting at a bus stop and fired on police before he was detained by Israeli security forces, officials said.
The victim was identified as a 32-year-old father of five from a nearby West Bank settlement. The attack took place at an intersection in the northern West Bank, near the Palestinian city of Nablus.
Israeli police spokesman Micky Rosenfeld said the assailant stabbed the Israeli and took his gun, then opened fire at border police nearby. The officers returned fire, wounding the Palestinian who was then detained. The Israeli man died of his wounds at the scene, Rosenfeld said.
Netanyahu latter expressed sorrow over the stabbing. "The terrorist who committed this murder was captured and we will continue to operate on that front to protect our citizens," he said.
A militant group claiming affiliation with the Al Aqsa Martyrs' Brigades, a violent offshoot of Palestinian President Mahmoud Abbas' Fatah, movement took responsibility for the stabbing attack in notices posted on the Internet.
The stabbing was the first fatal attack on Israelis in the West Bank since September 2011. Capt. Barak Raz, a military spokesman, said the area has experienced a rise in rock throwing and firebombing in recent months.
The Israeli military said that following the stabbing, settlers began rioting, hurling rocks at Palestinian vehicles and setting fire to nearby fields. It said two settlers were arrested.
Chris Dixon joined our co-editor Eric Eldon this morning at Disrupt NY 2013 to discuss his move out to San Francisco for a job at Andreessen Horowitz. One of the areas that interests him the most is the much-hyped Bitcoin space. The reason why Dixon is so interested is because it solves many problems for those who have tried to start a financial company in the past. He said: “There’s the whole problem of fraud online, which is a massive problem, along with all of the payment fees. The interesting thing with these math-based currencies is that you can do transactions without trusting the person at all.” He went on to discuss the beauty of Bitcoin, mostly the anonymous aspect of it, requiring no authentication or trust on either side of a transaction. Dixon stated: “The Internet is an anonymous network, but it requires authenticating identity. The exciting thing about these new currency schemes is that you have these anonymous payment systems grafted onto anonymous networks.” An example of the type of companies that Dixon is interested in investing in when it comes to Bitcoin are the companies like “Pay For Bits,” who would like to be the PayPal of Bitcoin. Due to regulations alone, there’s been a massive wall in between startups and doing something like this with actual money. Dixon feels like the best entrepreneurs on both coasts will probably start getting into Bitcoin and that means that we’ll see more innovation in the space. While top entrepreneurs won’t necessarily jump off of what they’re doing to start a Bitcoin company, but there are elements of the anonymous currency that could creep into existing products. For example, Reddit added Bitcoin as an option to purchase gold on the site, and we’ll have to see more of those types of things happen before the real products and investing starts.
<strong>"666 Park Ave.," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: <a href="http://www.huffingtonpost.com/2012/11/16/666-park-avenue-canceled_n_2147290.html">ABC pulled the plug</a> on this supernatural drama earlier in the season.
"The Bachelor"
<strong>"The Bachelor," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: While ratings may have dropped, "The Bachelor" will likely see another season on ABC as tabloids and viewers still care about the comings and goings of contestants.
"Body of Proof"
<strong>"Body of Proof," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: ABC is keen on this Dana Delany drama, but the ratings for this upcoming third season will be the true test.
"Castle"
<strong>"Castle," ABC</strong> <strong>Status</strong>: Likely to be renewed. <strong>Why</strong>: Strong ratings and a dedicated viewership will keep "Castle" on the schedule.
"Dancing With the Stars"
<strong>"Dancing With the Stars," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: The series is hurting in the ratings ... by "DWTS" standards. It's still a strong player for ABC, but the new season hasn't premiered yet.
"Don't Trust The B---- In Apt. 23"
<strong>"Don't Trust The B---- In Apt. 23," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: <a href="http://www.huffingtonpost.com/2013/01/22/apartment-23-canceled-dont-trust-the-b_n_2528858.html">ABC pulled the low-rated comedy</a> from it schedule and the stars took to Twitter to announce the cancellation.
"Family Tools"
<strong>"Family Tools," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: This ABC comedy has yet to debut, but a May 1 premiere date doesn't look great.
"Grey's Anatomy"
<strong>"Grey's Anatomy," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: America still loves McDreamy and the goings on at Seattle Grace. Expect "Grey's" to return.
"Happy Endings"
<strong>"Happy Endings," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: Always the bubble show, never the surefire renewal hit. "Happy Endings" has suffered from many ratings ailments, including bad scheduling (<a href="http://www.huffingtonpost.com/2013/02/14/happy-endings-friday-abc_n_2683091.html">it's moving to Friday night</a>) and lack of promo. But this ahmahzing show has some serious fans that could keep it afloat for another season ... maybe on another network (a la "Cougar Town.")
"How To Live With Your Parents (For The Rest Of Your Life)"
<strong>"How To Live With Your Parents (For The Rest Of Your Life)," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: The ABC comedy starring Sarah Chalke has yet to debut, but its late season bow doesn't exactly bode well for its future.
"Last Man Standing"
<strong>"Last Man Standing," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Viewers still love Tim Allen! Paired with "Malibu Country," "Last Man Standing" has been performing well on Friday nights and <a href="http://www.huffingtonpost.com/2013/02/14/jonathan-taylor-thomas-last-man-standing-home-improvement_n_2686307.html">will soon see Allen's "Home Improvement" co-star Jonathan Tyler Thomas</a>.
"Last Resort"
<strong>"Last Resort," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: <a href="http://www.huffingtonpost.com/2012/11/16/last-resort-canceled-abc_n_2147316.html">ABC killed the Shawn Ryan drama</a> in late 2012.
"Malibu Country"
<strong>"Malibu Country," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: "Malibu Country" has been performing well on Friday nights. Lesson: Never underestimate the star power of Reba.
"The Middle"
<strong>"The Middle," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Now in its fourth season, "The Middle" is still pulling in more than 8 million viewers an episode as the anchor of ABC's Wednesday comedies.
"Mistresses"
<strong>"Mistresses," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: The drama, which is based on the UK series of the same name, just got a Monday, May 27 premiere date. Though the scheduling struggle doesn't bode well, the ABC drama does have Alyssa Milano and "Lost" alum Yunjin Kim leading the foursome.
"Modern Family"
<strong>"Modern Family," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: A fan favorite and Emmy darling, "Modern Family" will be back and will make ABC lots of money in syndication.
"Nashville"
<strong>"Nashville," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: Critical acclaim doesn't always equate to rating success. The show has stabilized in Nielsen ratings, but its future really depends on the strength of ABC's drama pilots.
"The Neighbors"
<strong>"The Neighbors," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: One of the few "hits" of the season, "The Neighbors" has found an audience and kept it pretty steadily week after week (<a href="http://www.huffingtonpost.com/2012/06/11/abc-shows-fall-tv-2012-2013_n_1581796.html">much to our dismay</a>).
"Once Upon a Time"
<strong>"Once Upon a Time," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: A ratings hit in its second season, "Once Upon a Time" is almost sure to be back for a third season full of fairytale adventures.
"Private Practice"
<strong>"Private Practice," ABC</strong> <strong>Status</strong>: Ended <strong>Why</strong>: The "Grey's Anatomy" spinoff said goodbye in January 2013.
"Red Widow"
<strong>"Red Widow," ABC</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: The show has a late February debut on ABC.
"Revenge"
<strong>"Revenge," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: "Revenge" has fallen out of critical favor and seen lower ratings in its new Sunday night home. But none of ABC's freshman dramas are doing well, so that works in the show's favor.
"Rookie Blue"
<strong>"Rookie Blue," ABC</strong> <strong>Status</strong>: Renewed <strong>Why</strong>: The Canadian co-production will return for a fourth season on ABC during the summer of 2013.
"Scandal"
<strong>"Scandal," ABC</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: Shonda Rhimes has another hit on her hands. Now in its second season, "Scandal" has benefited from word-of-mouth and has been rising in the ratings (even recently beating out its lead in "Grey's Anatomy"). A likable star -- Kerry Washington -- and continued buzz will keep "Scandal" on the schedule.
"Suburgatory"
<strong>"Suburgatory," ABC</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: The series started Season 2 off strong in the ratings, but its audience has slowly eroded. Its not the worst-performing ABC sitcom, but its buzziness has died down as well.
"Zero Hour"
<strong>"Zero Hour," ABC</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: The Anthony Edwards vehicle debuted to 6.3 million viewers with a 1.3 rating in the key 18-49 demographic, making it <a href="http://www.huffingtonpost.com/2013/02/15/zero-hour-ratings_n_2695800.html">the least-watched premiere for a scripted series in ABC's history</a>. Things only got worse from there.
"2 Broke Girls"
<strong>"2 Broke Girls," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: CBS renewed "2 Broke Girls" in March of 2013.
"The Amazing Race"
<strong>"The Amazing Race," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: As an Emmy and fan favorite, "The Amazing Race" has been a strong player for CBS.
"The Big Bang Theory"
<strong>"The Big Bang Theory," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: Now in its sixth season, "Big Bang" is reaching series-high ratings. Even up against reality powerhouse "American Idol," "The Big Bang Theory" has been delivering with crazy high numbers in the 18-49 demographic, beating out what was once Fox's juggernaut.
"Blue Bloods"
<strong>"Blue Bloods," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: The Tom Selleck-fronted police drama is a strong ratings performer for CBS on Fridays.
"Criminal Minds"
<strong>"Criminal Minds," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: As one of CBS's strong procedural players, the series has been steady in the ratings and will likely be renewed to help anchor a night and launch a new drama.
"CSI"
<strong>"CSI," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: Of the two "CSI" shows on the air, "CSI" is the stronger player in the TV landscape. The show is nowhere near its earlier ratings, but Ted Danson signed on for more and the show will be back.
"CSI: NY"
<strong>"CSI: NY," CBS</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: The spinoff series will be entering Season 10 in the 2013-2014 season. The ratings have faded over the years, but they're still pretty stable, especially for Fridays. It's a toss up, depending on how well CBS's development slate goes.
"Elementary"
<strong>"Elementary," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: One of the very few freshman series hits during the 2012-2013 TV season, CBS is very keen on this modern-day take on Sherlock Holmes. The audience has been steady and the network even gave it the post-Super Bowl timeslot.
"Golden Boy"
<strong>"Golden Boy," CBS</strong> <strong>Status</strong>: Too soon to tell <strong>Why</strong>: CBS certainly has a handsome star at the front of this cop drama, but its late season entry and Friday timeslot could be a hint toward CBS's confidence in the show.
"The Good Wife"
<strong>"The Good Wife," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: A former ratings champ, "The Good Wife" has slipped to series low ratings on Sunday nights. Blame football overrun, fan-detested storylines or too many guest stars, but "The Good Wife" has star power and critical praise, plus its nearing a good syndication sweet spot.
"Hawaii Five-0"
<strong>"Hawaii Five-0," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: In March, <a href="http://www.huffingtonpost.com/2013/03/27/the-good-wife-renewed-season-5_n_2965829.html" target="_hplink">CBS announced "Hawaii Five-0" received an early renewal along with several of its other popular programs</a>.
"How I Met Your Mother"
<strong>"How I Met Your Mother," CBS</strong> <strong>Status</strong>: Renewed <strong>Why</strong>: CBS handed out a ninth and final season to this comedy with the entire cast returning. Expect to meet the mother, finally.
"Made In Jersey"
<strong>"Made In Jersey," CBS</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: CBS pulled the plug on this legal drama very early on in the season because of low ratings.
"The Mentalist"
<strong>"The Mentalist," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: "The Mentalist" has fallen to mediocre ratings -- by CBS standards -- but it was nonetheless renewed in March of 2013.
"Mike & Molly"
<strong>"Mike & Molly," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: The ratings are down a little bit from last year, but Melissa McCarthy's star continues to rise.
"NCIS"
<strong>"NCIS," CBS</strong> <strong>Status</strong>: Renewed <strong>Why</strong>: CBS reached a deal with series star Mark Harmon in early 2013, keeping the No. 1 show in America around for a Season 11.
"NCIS: LA"
<strong>"NCIS: LA," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: Viewers love their "NCIS," in any form. The ratings have been strong and the network is producing a backdoor spinoff pilot for this spinoff show. A full night of "NCIS" could be in CBS's future.
"Partners"
<strong>"Partners," CBS</strong> <strong>Status</strong>: Canceled <strong>Why</strong>: Low ratings and unfavorable reviews led to the <a href="http://www.huffingtonpost.com/2012/11/16/partners-canceled-cbs_n_2145832.html">early demise</a> of this CBS comedy.
"Person of Interest"
<strong>"Person of Interest," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: The series has developed a nice-sized audience, bigger than its first season.
"Rules of Engagement"
<strong>"Rules of Engagement," CBS</strong> <strong>Status</strong>: Honestly, who knows <strong>Why</strong>: This comedy has been on the bubble since it premiered ... yet is now in its seventh season. It's too soon to look at the numbers for this season, but the show has been a midseason success for CBS in the past. However, series co-star <a href="http://insidetv.ew.com/2013/02/07/cbs-orders-comedy-pilot-starring-patrick-warburton/">Patrick Warburton is attached to star in a new pilot</a> ... for CBS.
"Survivor"
<strong>"Survivor," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: A strong player for the last 13 years, "Survivor" will be back. But due to its <a href="http://www.huffingtonpost.com/2013/02/14/survivor-ratings-lowest-premiere-ever_n_2687591.html">most recent premiere ratings</a>, we might not see it during the fall season, though a midseason or summer return -- with some new gimmick -- is definitely in the cards for the reality series.
"Two and a Half Men"
<strong>"Two and a Half Men," CBS</strong> <strong>Status</strong>: Likely to be renewed <strong>Why</strong>: CBS wants another season of this bawdy hit, it's just a matter of getting its stars to sign back on.
"Undercover Boss"
<strong>"Undercover Boss," CBS</strong>
<strong>Status</strong>: Renewed
<strong>Why</strong>: The show is enjoying life in syndication and its Season 4 numbers are better than most of its third season.
"Unforgettable"
<strong>"Unforgettable," CBS</strong> <strong>Status</strong>: Uncanceled <strong>Why</strong>: CBS canceled the Poppy Montgomery drama last season ... and then revived it! Season 2 premieres Sunday, July 28.
"Vegas"
<strong>"Vegas," CBS</strong> <strong>Status</strong>: On the bubble <strong>Why</strong>: Despite star power, the series hasn't been a breakout hit in the ratings. CBS previously canceled "Unforgettable" (then uncanceled it) last season when it was doing about the same as "Vegas."
Cat and mouse: A single gene mattersPublic release date: 29-Apr-2013 [ | E-mail | Share ]
Contact: Megan Fellman fellman@northwestern.edu 847-491-3115 Northwestern University
Scientists discover 1 gene is necessary for mice to avoid predators
When a mouse smells a cat, it instinctively avoids the feline or risks becoming dinner. How? A Northwestern University study involving olfactory receptors, which underlie the sense of smell, provides evidence that a single gene is necessary for the behavior.
A research team led by neurobiologist Thomas Bozza has shown that removing one olfactory receptor from mice can have a profound effect on their behavior. The gene, called TAAR4, encodes a receptor that responds to a chemical that is enriched in the urine of carnivores. While normal mice innately avoid the scent marks of predators, mice lacking the TAAR4 receptor do not.
The study, published April 28 in the journal Nature, reveals something new about our sense of smell: individual genes matter.
Unlike our sense of vision, much less is known about how sensory receptors contribute to the perception of smells. Color vision is generated by the cooperative action of three light-sensitive receptors found in sensory neurons in the eye. People with mutations in even one of these receptors experience color blindness.
"It is easy to understand how each of the three color receptors is important and maintained during evolution," said Bozza, an author of the paper, "but the olfactory system is much more complex."
In contrast to the three color receptors, humans have 380 olfactory receptor genes, while mice have more than 1,000. Common smells like the fragrance of coffee and perfumes typically activate many receptors.
"The general consensus in the field is that removing a single olfactory receptor gene would not have a significant effect on odor perception," said Bozza, an assistant professor of neurobiology in the Weinberg College of Arts and Sciences.
Bozza and his colleagues tested this assumption by genetically removing a specific subset of olfactory receptors called trace amine-associated receptors, or TAARs, in mice. Mice have 15 TAARs. One is expressed in the brain and responds to amine neurotransmitters and common drugs of abuse such as amphetamine. The other 14 are found in the nose and have been coopted to detect odors.
Bozza's group has shown that the TAARs are extremely sensitive to amines -- a class of chemicals that is ubiquitous in biological systems and is enriched in decaying materials and rotting flesh. Mice and humans typically avoid amines since they have a strongly unpleasant, fishy quality.
Bozza's team, including the paper's lead authors, postdoctoral fellow Adam Dewan and graduate student Rodrigo Pacifico, generated mice that lack all 14 olfactory TAAR genes. These mice showed no aversion to amines. In a second experiment, the researchers removed only the TAAR4 gene. TAAR4 responds selectively to phenylethylamine (PEA), an amine that is concentrated in carnivore urine. They found that mice lacking TAAR4 fail to avoid PEA, or the smell of predator cat urine, but still avoid other amines.
"It is amazing to see such a selective effect," Dewan said. "If you remove just one olfactory receptor in mice, you can affect behavior."
The TAAR genes are found in all mammals studied so far, including humans. "The fact that TAARs are highly conserved means they are likely important for survival," Bozza said.
One idea is that the TAARs may make animals very sensitive to the smell of amines. Humans may have TAAR genes to avoid rotting foods, which become enriched in amines during the decomposition process. In fact, the TAARs may relay information to a specific part of the brain that elicits innately aversive behavior in animals.
Bozza's lab has recently shown that neurons in the nose that express the TAARs connect to with a specific region of the olfactory bulb -- the part of the brain that first receives olfactory information. This suggests that the TAARs may elicit hardwired responses to amines in mice, and perhaps humans.
"We hope this work will reveal specific brain circuits that underlie instinctive behaviors in mammals," Bozza said. "Doing so will help us understand how neural circuits contribute to behavior."
###
The paper is entitled "Non-redundant coding of aversive odours in the main olfactory pathway." In addition to Bozza, Dewan and Pacifico, the paper is co-authored by Ross Zhan, an undergraduate student at Northwestern, and Dmitry Rinberg, from the Howard Hughes Medical Institute Janelia Farm Research Campus.
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Cat and mouse: A single gene mattersPublic release date: 29-Apr-2013 [ | E-mail | Share ]
Contact: Megan Fellman fellman@northwestern.edu 847-491-3115 Northwestern University
Scientists discover 1 gene is necessary for mice to avoid predators
When a mouse smells a cat, it instinctively avoids the feline or risks becoming dinner. How? A Northwestern University study involving olfactory receptors, which underlie the sense of smell, provides evidence that a single gene is necessary for the behavior.
A research team led by neurobiologist Thomas Bozza has shown that removing one olfactory receptor from mice can have a profound effect on their behavior. The gene, called TAAR4, encodes a receptor that responds to a chemical that is enriched in the urine of carnivores. While normal mice innately avoid the scent marks of predators, mice lacking the TAAR4 receptor do not.
The study, published April 28 in the journal Nature, reveals something new about our sense of smell: individual genes matter.
Unlike our sense of vision, much less is known about how sensory receptors contribute to the perception of smells. Color vision is generated by the cooperative action of three light-sensitive receptors found in sensory neurons in the eye. People with mutations in even one of these receptors experience color blindness.
"It is easy to understand how each of the three color receptors is important and maintained during evolution," said Bozza, an author of the paper, "but the olfactory system is much more complex."
In contrast to the three color receptors, humans have 380 olfactory receptor genes, while mice have more than 1,000. Common smells like the fragrance of coffee and perfumes typically activate many receptors.
"The general consensus in the field is that removing a single olfactory receptor gene would not have a significant effect on odor perception," said Bozza, an assistant professor of neurobiology in the Weinberg College of Arts and Sciences.
Bozza and his colleagues tested this assumption by genetically removing a specific subset of olfactory receptors called trace amine-associated receptors, or TAARs, in mice. Mice have 15 TAARs. One is expressed in the brain and responds to amine neurotransmitters and common drugs of abuse such as amphetamine. The other 14 are found in the nose and have been coopted to detect odors.
Bozza's group has shown that the TAARs are extremely sensitive to amines -- a class of chemicals that is ubiquitous in biological systems and is enriched in decaying materials and rotting flesh. Mice and humans typically avoid amines since they have a strongly unpleasant, fishy quality.
Bozza's team, including the paper's lead authors, postdoctoral fellow Adam Dewan and graduate student Rodrigo Pacifico, generated mice that lack all 14 olfactory TAAR genes. These mice showed no aversion to amines. In a second experiment, the researchers removed only the TAAR4 gene. TAAR4 responds selectively to phenylethylamine (PEA), an amine that is concentrated in carnivore urine. They found that mice lacking TAAR4 fail to avoid PEA, or the smell of predator cat urine, but still avoid other amines.
"It is amazing to see such a selective effect," Dewan said. "If you remove just one olfactory receptor in mice, you can affect behavior."
The TAAR genes are found in all mammals studied so far, including humans. "The fact that TAARs are highly conserved means they are likely important for survival," Bozza said.
One idea is that the TAARs may make animals very sensitive to the smell of amines. Humans may have TAAR genes to avoid rotting foods, which become enriched in amines during the decomposition process. In fact, the TAARs may relay information to a specific part of the brain that elicits innately aversive behavior in animals.
Bozza's lab has recently shown that neurons in the nose that express the TAARs connect to with a specific region of the olfactory bulb -- the part of the brain that first receives olfactory information. This suggests that the TAARs may elicit hardwired responses to amines in mice, and perhaps humans.
"We hope this work will reveal specific brain circuits that underlie instinctive behaviors in mammals," Bozza said. "Doing so will help us understand how neural circuits contribute to behavior."
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The paper is entitled "Non-redundant coding of aversive odours in the main olfactory pathway." In addition to Bozza, Dewan and Pacifico, the paper is co-authored by Ross Zhan, an undergraduate student at Northwestern, and Dmitry Rinberg, from the Howard Hughes Medical Institute Janelia Farm Research Campus.
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Derya Sert, a 22-year-old Turkish woman, is officially six-weeks into a normal, healthy pregnancy. The absolutely remarkable part? Sert was born without a womb and received the first successful uterus transplant ever.
WASHINGTON (AP) ? The U.S. and its allies are still trying to figure out details of Syria's suspected use of chemical weapons against its own people, Defense Secretary Chuck Hagel said Monday, as international officials pressed for broader access to suspected attack sites.
Speaking to Pentagon reporters, Hagel refused to discuss any military options including whether or not the U.S. would be willing to take unilateral action against the Syrian regime or if the administration would act only in concert with allies.
The Obama administration said last week that U.S. intelligence had concluded that Syrian government forces likely used chemical agents against rebels in two attacks, but said there were "varying degrees of confidence" about how large an attack it may have been.
Since then the administration has come under withering criticism from members of Congress demanding that the U.S. take steps to protect the Syrian people by setting up either a safe zone or a no-fly zone over at least parts of the country.
"We are continuing to assess what happened -- when, where," said Hagel. "I think we should wait to get the facts before we make any judgments on what action, if any should be taken, and what kind of action."
U.S. officials, including Secretary of State John Kerry, have said that chemical weapons ? likely the nerve agent sarin ? were used on two occasions.
Syria wants any investigation limited to an incident in the Khan al-Assal village in the Aleppo province in March that reportedly killed 31 people, but U.N. Secretary-General Ban Ki-moon wants a broader investigation, that would include a December incident in Homs.
Britain, France, Israel and Qatar also believe chemical weapons have been used in Syria's two-year-old civil war. President Barack Obama has said that use of chemical weapons by President Bashar Assad's regime, or the transfer of those stockpiles to terrorists would cross a "red line" and have "enormous consequences."
LONDON (Reuters) - Britain is considering giving energy consumers living near shale gas exploration sites access to cheaper bills, the government said on Monday, to help soften their reaction to drilling work on their doorstep.
Britain is counting on untapped reserves of shale gas trapped in rock formations to help reduce its growing dependence on energy imports.
"This is one of several options we are looking at," said a spokesman for the Department of Energy and Climate Change.
He also said investment into community facilities such as sports centres were part of the discussions.
"We will publish a report in the summer," he said, building on comments made last month by Chancellor George Osborne, promising local community benefits from shale gas exploration and huge tax breaks for explorers.
British shale gas firmCuadrilla Resources said it was in discussions with local communities and the government to identify schemes through which residents can benefit from shale gas.
Public opposition against large infrastructure projects has been widespread in Britain.
Onshore wind farm developers have struggled to gain local planning approval in more populated areas as residents rebelled against the construction of wind turbines, which they called noisy and obtrusive.
The practice of offering community benefits is now widespread in the onshore wind industry. Examples include energy bill rebates for residents directly affected by the construction of wind farms.
(Reporting by Karolin Schaps; Additional reporting by Oleg Vukmanovic, editing by William Hardy)
Apr. 29, 2013 ? A team of bioengineers at Brigham and Women's Hospital (BWH) is the first to report creating artificial heart tissue that closely mimics the functions of natural heart tissue through the use of human-based materials. Their work will advance how clinicians treat the damaging effects caused by heart disease, the leading cause of death in the United States.
"Scientists and clinicians alike are eager for new approaches to creating artificial heart tissues that resemble the native tissues as much as possible, in terms of physical properties and function," said Nasim Annabi, PhD, BWH Renal Division, first study author. "Current biomaterials used to repair hearts after a heart attack and other cardiovascular events lack suitable functionality and strength. We are introducing an alternative that has the mechanical properties and functions of native heart tissue."
The study was published online on April 26, 2013 in Advanced Functional Materials.
The researchers created MeTro gel-an advanced rubber-like material made from tropoelastin, the protein in human tissues that makes them elastic. The gel was then combined with microfabrication techniques to generate gels containing well-defined micropatterns for high elasticity.
The researchers then used these highly elastic micropatterned gels to create heart tissue that contained beating heart muscle cells.
"The micropatterned gel provides elastic mechanical support of natural heart muscle tissue as demonstrated by its ability to promote attachment, spreading, alignment, function and communication of heart muscle cells," said Annabi.
The researchers state that MeTro gel will provide a model for future studies on how heart cells behave. Moreover, the work lays the foundation for creating more elaborate 3D versions of heart tissue that will contain vascular networks.
"This can be achieved by assembling tandem layers of micropatterned MeTro gels seeded with heart muscles cells in different layers," said Ali Khademhosseini, PhD, BWH Division of Biomedical Engineering, co-senior study author. "As we continue to move forward with finding better ways to mend a broken heart, we hope the biomaterials we engineer will allow us to successfully address the limitations of current artificial tissues."
This research was supported by the National Institutes of Health (HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392); National Health and Medical Research Council; CRC for Polymers; BHP-Billiton Fulbright Scholarship; National Science Foundation; Office of Naval Research Young National Investigator Award; Presidential Early Career Award for Scientists and Engineers; Australian Research Council; and Australian Defense Health Foundation and National Health and Medical Research Council.
Anthony Weiss, PhD, University of Sydney, co-senior study author is scientific founder of Elastagen Pty Ltd.
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The above story is reprinted from materials provided by Brigham and Women's Hospital.
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Journal Reference:
Nasim Annabi, Kelly Tsang, Suzanne M. Mithieux, Mehdi Nikkhah, Afshin Ameri, Ali Khademhosseini, Anthony S. Weiss. Highly Elastic Micropatterned Hydrogel for Engineering Functional Cardiac Tissue. Advanced Functional Materials, 2013; DOI: 10.1002/adfm.201300570
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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
PESHAWAR, Pakistan ? A suicide bomber targeting a police van killed six people in northwestern Pakistan on Monday, including the son and nephew of an Afghan official involved in peace negotiations with the Taliban, officials said.
The bomber, who was riding a motorcycle, detonated his explosives as the police patrol drove by in the northwestern city of Peshawar, said city police chief Liaqat Ali Khan.
The two Afghans who were killed ? Qazi Mohammad Hilal Waqad and Mohammad Idrees ? were working at their country's consulate in Peshawar where the attack occurred, said Afghan Consul General Syed Mohammad Ibrahim Khel in Islamabad.
However, it did not appear they were the target of the attack, Khel said.
Waqad's father, Qazi Amin Waqad, is a member of the Afghan High Peace Council, a group appointed by the Afghan government to hold peace negotiations with the Taliban, said an official at the consulate in Peshawar, Shakir Qarar.
The peace council member was in Afghanistan when the attack occurred, while Waqad and Idrees were driving to work when the bomber struck, Qarar added.
Three policemen were among over 30 people who were wounded by the blast, said the police chief, Khan. Many of the dead and wounded were from a nearby passenger bus, which bore the brunt of the attack.
Local TV footage showed the wreckage of the bus and the motorcycle, as rescue workers rushed wounded people to hospitals in the city.
No one immediately claimed responsibility, but suspicion will likely to fall on the Pakistani Taliban. The group has been waging a bloody insurgency against the government for years and has stepped up attacks ahead of next month's parliamentary election.
On Sunday, the Taliban killed 11 people in bomb attacks on a political rally and two campaign offices in the northwest, part of their quest to disrupt the election. The group has killed at least 60 people in attacks on politicians and party workers since the beginning of April.
The Taliban have specifically targeted more secular political parties that have supported military offensives against the militants in the northwest. The Taliban have largely spared Islamic parties and others who believe the government should strike a peace deal with the militants, rather than fight them.
There is a concern that the violence could benefit the parties that take a softer line toward the militants because they are able to campaign more freely ahead of the May 11 election.
"Unless the government, the country's independent election commission and security forces ensure that all parties can campaign freely without fear, the election may be severely compromised," Ali Dayan Hasan, the head of Human Rights Watch in Pakistan, said in a statement issued Monday.
IRVING, Texas (AP) ? Inbee Park was already preparing to congratulate Carlota Ciganda for winning the inaugural North Texas LPGA Shootout.
Park, the top-ranked woman in the world, was in the middle of a solid final round and still trailed by two strokes after the playing partners both had birdies at the par-5 10th on Sunday.
Everything changed in a two-hole stretch, when Park went ahead with consecutive pars. The 24-year-old South Korean went on to a bogey-free 4-under 67 that put her one stroke ahead of Ciganda, good enough for her third victory this season and fifth in her last 18 starts.
"She was hitting fairways and greens and making putts," said Park, who finished at 13 under. "And I thought I played really great today, but I just missed a lot of birdie opportunities, so I thought this tournament might not be mine because I missed that many opportunities and Carlota was playing great golf. But she made a couple mistakes on the back nine."
Ciganda's drive at the 416-yard 14th hole settled in the right rough with a tree between her and the green, and her shot from about 130 yards clipped a branch and came up short. She had a chance to save par but her 6-foot putt was short, and Park's par had her within a stroke of the lead.
After stepping away from her approach at No. 15, to a green surrounded by water on three sides, Ciganda hit a shot that went to the right and then rolled down into the water. Ciganda had to go back to a drop zone, where the 22-year-old Spaniard had a decent pitch before her first putt rolled over the left edge of the green for a double bogey 6.
Park had another par and never trailed again.
"I'm very happy with my round and with my week. ... I had two bad holes on the back nine," Ciganda said.
With the $195,000 check for first place, Inbee exceeded $6 million in career earnings and will be No. 1 for the third week in a row. It was her sixth career LPGA victory, along with four more wins in Japan.
Fifth-ranked Suzann Pettersen from Norway, the winner in Hawaii last week, had a closing 66 to get to 10 under and finish third. Hee Young Park (64) and So Yeon Ryu (68) tied for fourth at 275.
Ciganda played last season on the Ladies European Tour, where she was the top rookie and the top money winner ? the first player since Laura Davies in 1985 to accomplish that feat. She won twice in Europe last year and now has her best LPGA finish.
At the 403-yard 8th hole, Park made a birdie before Ciganda followed with one of her own and responded with a slight fist pump when her ball dropped into the cup. They both had pars at No. 9, where Park was closer to the hole even though she was missed the green to the left, and they traded birdies again at the par-5 10th.
"I was happy and playing good and having fun and enjoying the day," said Ciganda, who had a closing 70. "And then I think, let me see, the hole it bounced to the right, but I had a bogey there and then hit it to the water on 15."
Caroline Masson had a 75 and finished eight shots back. The LPGA Tour rookie from Germany led after each of the first two rounds and started the final round tied for second with Park.
Hee Young Park's 64 was the best round of the day on the 6,439-yard course with plenty of sloping fairways and raised greens.
Stacy Lewis, the Texas native and No. 2 player in the world, had a closing 66 when all six birdies and her only bogey came between Nos. 7-17. She tied for seventh for her sixth top-10 finish this season.
At the end of her round, Lewis signed the back brace of a 6-year-old Dallas girl who was diagnosed with scoliosis at 18 months old. Lewis wore a similar brace 18 hours a day for seven years after being diagnosed with scoliosis at age 11 and missed her first collegiate season after a spinal fusion.
Third-ranked Na Yeon Choi, among the four players tied for seventh, had 44 consecutive bogey-free holes and was 9 under before consecutive bogeys at Nos. 10-12. She went on to a 72.
Inbee Park sank a 4-foot birdie putt on the par-5 18th after Ciganda also birdied even after her final drive went into the right rough. But they had an unusual wait after hitting their drives, when Jee Young Lee, playing two groups ahead of them, had to replay the hole.
Before Lee signed her scorecard, officials determined she took an improper drop after her drive at No. 18 went out of bounds. Lee carded a 10 before Ciganda and Park got to play out the hole.
"It was all right. I mean it was actually really good, it ended up really good for me because I made a birdie," Park said of the delay. "Maybe if I hit it in the water maybe I could have blamed it on them."
The Xerox Phaser 7100/N is a new model in Xerox's repertoire, filling a niche as a relatively low-cost color laser printer that can print at up to tabloid size (11 by 17 inches). In that role it's a winner, with good speed and strong output quality, led by above-par graphics and slightly above-average photos. It earns an Editors' Choice for budget color laser printer.
The 7100/N lacks the natural-language color control of the Editors' Choice Xerox Phaser 7500/DN and is not designed for as massive print volumes--with a maximum monthly duty cycle of 52,000 pages, compared with the 7500/DN's 150,000 pages. It can't quite match the 7500/DN's exceptional output quality. But it brings enough to the table to become an Editors' Choice in its own right as a lower-priced tabloid color laser printer.
The two-tone (blue and white) 7100/N measures 16 by 21 by 19.7 inches (HWD) and weighs 97 pounds, so you'll need at least two people to move it into place. Still, it's lighter than the 145-pound Xerox 7500/DN. The 7100/N has a 400-sheet standard paper capacity, between a 250-sheet main tray and a 150-sheet secondary tray, both of which can fit tabloid-size (11 by 7) paper. The 7100/N lacks an automatic duplexer; another model, the 7100/DN ($1,800 direct), includes a duplexer. Up to three additional 550-sheet trays ($399 each) are available as options, as is a wireless adapter ($219), and a productivity kit whose centerpiece is a 40GB hard drive ($499).
The Xerox Phaser 7100/N has standard Ethernet and USB connectivity. I tested the Phaser over an Ethernet connection with a PC running Windows Vista. The recommended driver, which installs by default, is PostScript; users can also install PCL emulations, PDF Direct, or XPS drivers. I ran all our tests using the default PostScript driver.
Speed
I timed the Xerox Phaser 7100/N on the latest version of our business applications suite (as timed with QualityLogic's hardware and software), at 7.6 effective pages per minute (ppm) a good speed considering its rated print speed of 30 ppm. (Rated speeds are based on text-only printing, while our test suite combines text pages, graphics pages, and pages with mixed content.) It even edges out the Xerox Phaser 7500/DN, rated at 35 pages per minute for both color and black-and-white printing, which we timed at 7.1 ppm. I clocked the Dell 7130cdn Color Printer
, rated at 35 ppm for monochrome printing and 30 ppm for color printing, at 8.3 ppm.
Output Quality
The Phaser 7100/N's text was average for lasers, which is still good enough for most every business document except for uses such as demanding desktop publishing applications requiring very small fonts.
Graphics quality is above par; graphics should be fine for any internal business use, including PowerPoint handouts, and could be used for basic marketing materials. Flaws, all minor, included some mild blotchiness in dark backgrounds, and dithering (graininess).
Photo quality was slightly above average. Most of the prints could pass as true photo quality when seen under glass at arm's length. There was some loss of detail in bright areas, and one image showed traces of banding (spurious, slightly dark streaks). The quality is easily good enough to use in company or client newsletters, and is perhaps up to use in basic advertising handouts, depending on how picky you are.
Comparison
As a budget color laser that can print up to tabloid size, the Xerox Phaser 7100/N offers good speed and good overall output quality, with above-average graphics and slightly above-par photos. The 7100/N lacks natural language software color control, one of our favorite features from the Xerox 7500/DN. Accessible through the printer's drivers, it lets people with no technical knowledge of color mixing easily tweak colors from print to print by using a series of drop-down menus, with commands such as "green colors slightly more green."
The 7100/N's output quality?though solid, with particularly good graphics quality?can't match that of the 7500/DN, which was top tier for photos and graphics and just short of top tier for text. The 7500/DN also has great paper capacity (600 sheets standard, plus auto-duplexer). The 7100/N did manage to edge the 7500/DN in printing speed, however.
The Dell 7130cdn, essentially the same printer as the Xerox 7500/DN except lacking natural-language color control, is a tad faster than the other two printers. Its output quality was similar to the 7100/N's, except the Xerox printed superior graphics in our testing. And it costs more than $1,000 more than the 7100/N.
Although the Xerox Phaser 7100/N can't match the Phaser7500/DN in features and output quality, you can get it for less than half the price, a bargain for a tabloid color laser printer. So while the 7500/DN remains the Editors' Choice as a high-end color laser tabloid printer, the 7100/N is a new Editors' Choice as a budget model. Not only is it cost effective, it adds good speed and output quality, and should be a welcome addition to small or mid-sized offices or workgroups looking for a color laser that can print at tabloid size.
LONDON (Reuters) - A mother who persuaded her adopted teenage daughter to become pregnant by artificial insemination because she wanted a baby for herself has been jailed for five years in Britain, in a case that raises concern over how easily donor sperm can be obtained.
Previously secret court documents showed that the daughter, a virgin, was made to inseminate herself alone in her bedroom seven times over a two-year period starting in 2008 when she was 14, using syringes of semen bought online by the mother from sperm bank Cryos in Denmark.
She eventually became pregnant at 16 and gave birth at 17. The extraordinary circumstances of her pregnancy came to light after midwives became suspicious of the mother because she was trying to prevent her daughter from bonding with the new baby.
"We don't want any of that attachment thing," the mother said when a midwife suggested that the girl might want to breastfeed. After several such incidents the midwives alerted social services and police got involved in July 2011.
In a ruling made in March 2012 but only published now after the conclusion of the mother's criminal trial, High Court Judge Peter Jackson described "an abiding sense of disbelief that a parent could behave in such a wicked and selfish way towards a vulnerable child".
The judge also raised questions about the international trade in donor sperm, noting that "there were no effective checks on a person's ability to obtain sperm from Cryos".
There is no law in Britain to stop someone from buying donor sperm on the Internet and using it at home without supervision.
The Human Fertilisation and Embryology Authority (HFEA) said it was "shocked and appalled by this dreadful case" and would be discussing with the Department of Health the issues raised relating to the donation of sperm.
Described in the judgment as having "an exceptionally forceful personality", the mother wanted to be the sole influence in the lives of her daughters, whom she schooled at home behind drawn curtains and kept isolated from the world.
The mother, who was imprisoned for child cruelty, had three adopted daughters but desperately wanted a fourth and was distraught when authorities told her in 2007 that she would not receive approval for a further adoption.
Instead, she persuaded the eldest of her three daughters to embark on a program of artificial insemination to provide her with a baby to raise as her own.
The mother wanted the child to be a girl and made her daughter use acid douches containing vinegar or lemon juice in the belief that this would influence an unborn child's gender.
The daughter said she allowed her body to be used by her mother because she loved her. In a Mother's Day card written in 2009, the daughter pasted a photo of a positive pregnancy test and promised that she would give her mother that.
Cryos declined to comment on the case or on its procedures. In a section on home insemination, the sperm bank's website says: "In EU the goods can freely be moved from country to country, however, Cryos cannot know the rules in all countries so the recipient is responsible for the legality of imports."
The NY Post is reporting that "at least two major hedge funds" have amassed significant stakes in troubled, near dead, strategically challenged retailer JC Penney. The news comes on the heels of last week's SEC filing from George Soros revealing a 7.9% stake in JC Penney (JCP) stock.
Adding to the JC Penney positive news from earlier this morning, the company confirms it secured a $1.75 billion financing package from Goldman Sachs (GS). The terms have been rumored to be a remarkably generous 7%.
A whopping 36.8% of JC Penney's float was short as of April 15th. A big part of the short thesis had been the very real possibility that the company wouldn't have the liquidity to make it to the Christmas buying season.
Between the Post's unnamed funds and Soros, the timing of the stock purchases are curious if not flat out suspicious. JC Penney had been known to be looking for loans for months, and Goldman no doubt shopped the deal around the Street to find indications of interest.
JC Penney stock has been locked in the mid-teens for almost two months. So much smart money jumping in all at once is curious if not a smoking gun. Knowing the deal was likely to get done would have made the $15 area a low-risk entry point.
The company still has a laundry list of problems, but at least for the moment liquidity isn't one of them. "This company obviously has a lifeline now," says Yahoo Senior Columnist Michael Santoli in the attached clip. "You can kind of make the case that if JCPenney can at all stop the bleeding, maybe there's value there." Nothing beats a couple billion dollars at favorable rates when it comes to stanching a cash bleed.
"The stock bottomed, it looks now around $15 and now we're about $17 somewhere," notes Santoli, and that the company "really [hasn't] done much of anything but get out of that death-watch zone in terms of price." When a company has been as bad as JC Penney, achieving a stable vegetative state can be enough to take shares farther than would seem logical.
Chief of Staff Gen. Raymond T. Odierno, from left, Michael Scherer, White House correspondent for TIME, late-night television host Conan O'Brien and first lady Michelle Obama attend the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)
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Comedian Conan O'Brien (L) smiles as US President Barack Obama (C) and US first lady Michelle Obama arrive for the White House Correspondents? Association Dinner April 27, 2013 in Washington, DC. Obama attended the yearly dinner which is attended by journalists, celebrities and politicians. AFP PHOTO/Brendan SMIALOWSKI (Photo credit should read BRENDAN SMIALOWSKI/AFP/Getty Images)
Barack Obama
President Barack Obama looks to the podium during the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)
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Comedian Conan O'Brien (L) and US first lady Michelle Obama joke during the White House Correspondents? Association Dinner April 27, 2013 in Washington, DC. Obama attended the yearly dinner which is attended by journalists, celebrities and politicians. AFP PHOTO/Brendan SMIALOWSKI (Photo credit should read BRENDAN SMIALOWSKI/AFP/Getty Images)
Barack Obama, Conan O'Brien, Michelle Obama, Michael Clemente
Late-night television host Conan O'Brien, from left, first lady Michelle Obama, Michael Clemente, Executive Vice President of Fox News, and President Barack Obama attend the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)
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Comedian Conan O'Brien listens during the White House Correspondents? Association Dinner April 27, 2013 in Washington, DC. Obama attended the yearly dinner which is attended by journalists, celebrities and politicians. AFP PHOTO/Brendan SMIALOWSKI (Photo credit should read BRENDAN SMIALOWSKI/AFP/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Alicia Quarles attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Megan Hilt attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Morena Baccarin attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Musician John Legend attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Model Chrissy Teigen attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
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Entertainer John Legend arrives at the annual White House Correspondents' Association dinner in Washington DC, April 27, 2013. AFP Photo/ Chris KLEPONIS (Photo credit should read CHRIS KLEPONIS/AFP/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Musician Psy attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
Steven Spielberg
Director Steven Spielberg uses his smart phone during the White House Correspondents' Association Dinner at the Washington Hilton Hotel, Saturday, April 27, 2013, in Washington. (AP Photo/Carolyn Kaster)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Amy Poehler attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Claire Danes attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Julia Louis-Dreyfus attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Kerry Washington attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Morena Baccarin attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Rebel Wilson and Olympic Gymnist Gabby Douglas attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Kate Mara attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Kate Mara attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Aasif Mandvi and Ty Burrel attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Al Sharpton and Chris Matthews attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Emily Mortimer attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Connie Britton attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Patricia Arquette attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: John Oliver and Kate Oliver attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actor Ryan Kwanten attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Jessica Pare attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actor Justin Bartha attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Julie Bowen attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: NFL player Victor Cruz (L) and Elaina Watley attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Ty Burrell attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Olivia Munn attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Olivia Munn attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
WASHINGTON, DC - APRIL 27: Jeffrey Katzenberg, Time Magazine Managing Editor Rick Stengel and Steven Spielberg attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Larry Busacca/Getty Images for Time, Inc)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Elizabeth Banks attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Elizabeth Banks attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Jessica Pare attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Aasif Mandvi attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Sofia Vergara attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Michelle Dockery attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actress Constance Zimmer attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actor Tony Goldwyn attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Thomas Roberts attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Actor Ed Helms attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Korie Robertson and Willie Robertson attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
WASHINGTON, DC - APRIL 27: Gerard Butler and Piers Morgan attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Larry Busacca/Getty Images for Time, Inc)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Matthew Perry attends the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
2013 White House Correspondents' Association Dinner
WASHINGTON, DC - APRIL 27: Piers Morgan and Gerard Butler attend the White House Correspondents' Association Dinner at the Washington Hilton on April 27, 2013 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)